Case Report: Maculopathy following standard dose intracameral cefuroxime injection during ICL surgery

While intracameral cefuroxime is a highly effective prophylactic against endophthalmitis, it may cause sporadic toxic maculopathy even at standard doses during ICL surgery. Unlike typical post-cataract inflammatory edema, ICOTS presents acutely on day 1. Surgeons should maintain a high index of suspicion and utilize early OCT imaging for unexpected postoperative visual disturbances.

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Publication Details

Journal
Frontiers in Ophthalmology
Published
2026-03-05
DOI
https://doi.org/10.3389/fopht.2026.1778421
Primary Topic
Ocular Infections and Treatments
Type
article
Field-Weighted Citation Impact
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OCT
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Case Report: Maculopathy following standard dose intracameral cefuroxime injection during ICL surgery

Li Huang, Jingning Weng, Zhenlin Lin, Shouchun Yi et al.
Frontiers in Ophthalmology
Ocular Infections and Treatments
article

Case Report: Maculopathy following standard dose intracameral cefuroxime injection during ICL surgery

Li Huang, Jingning Weng, Zhenlin Lin, Shouchun Yi, Deli Li
article en

Abstract

While intracameral cefuroxime is a highly effective prophylactic against endophthalmitis, it may cause sporadic toxic maculopathy even at standard doses during ICL surgery. Unlike typical post-cataract inflammatory edema, ICOTS presents acutely on day 1. Surgeons should maintain a high index of suspicion and utilize early OCT imaging for unexpected postoperative visual disturbances.

Frontiers in OphthalmologyVol. 6
He Eye Hospital (CN)
Gender equality
Openalex Percentile: Top 32%
Ocular Infections and Treatments
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