IL-17A rs2275913 polymorphism is associated with spinal tuberculosis but not with pulmonary tuberculosis: A study of the Han population in southern China
In the Han population of southern China, the IL-17 A rs2275913 was first identified as associated with susceptibility to STB, but not with susceptibility to PTB. This locus maybe a relatively specific genetic locus for STB. The A allele at this locus is a protective factor against STB and maybe one of the genetic factors determining which subtype of tuberculosis progresses.
Authors
- X B Wang (ORCID: https://orcid.org/0000-0002-8068-2616)
- Tao Li (ORCID: https://orcid.org/0000-0002-9233-8783)
- Chaofeng Guo
- Juan Luo
Institutions
- Central South University (CN)
- The Central Hospital of Shaoyang (CN)
- Xiangya Hospital Central South University (CN)
- Loudi Central Hospital (CN)
Publication Details
- Journal
- Infection Genetics and Evolution
- Published
- 2026-03-05
- DOI
- https://doi.org/10.1016/j.meegid.2026.105921
- Primary Topic
- Infectious Diseases and Tuberculosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00