Pseudo-renal failure with hyponatremia and proteinuria after gynecologic surgery: a case report with literature comparison

This case highlights the importance of recognizing pseudo-renal failure as a differential diagnosis of unexplained azotemia, particularly in patients with recent pelvic surgery. The coexistence of elevated serum creatinine with relatively preserved cystatin C, ascites, hyponatremia, and nephrotic-range proteinuria should raise suspicion for urinary tract injury. Measurement of ascitic fluid creatinine and CT cystography are key diagnostic tools for genitourinary trauma that can prevent unnecessary invasive procedures and guide timely therapeutic interventions. Ultimately, awareness of this entity enables prompt diagnosis and favorable clinical outcomes for patients.

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Publication Details

Journal
BMC Nephrology
Published
2026-03-05
DOI
https://doi.org/10.1186/s12882-026-04856-7
Primary Topic
Acute Kidney Injury Research
Type
article
Field-Weighted Citation Impact
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article

Pseudo-renal failure with hyponatremia and proteinuria after gynecologic surgery: a case report with literature comparison

E. Cho, H. J. Kim, Minwoo Kang, Seung Min Song et al.
BMC Nephrology
Acute Kidney Injury Research
article

Pseudo-renal failure with hyponatremia and proteinuria after gynecologic surgery: a case report with literature comparison

E. Cho, H. J. Kim, Minwoo Kang, Seung Min Song, Ji Eun Kim, Soojeong Yun, Gang Jee Ko, Young Joo Kwon, Shin Young Ahn
article en

Abstract

This case highlights the importance of recognizing pseudo-renal failure as a differential diagnosis of unexplained azotemia, particularly in patients with recent pelvic surgery. The coexistence of elevated serum creatinine with relatively preserved cystatin C, ascites, hyponatremia, and nephrotic-range proteinuria should raise suspicion for urinary tract injury. Measurement of ascitic fluid creatinine and CT cystography are key diagnostic tools for genitourinary trauma that can prevent unnecessary invasive procedures and guide timely therapeutic interventions. Ultimately, awareness of this entity enables prompt diagnosis and favorable clinical outcomes for patients.

BMC Nephrology
Korea University Medical Center (KR), Korea University (JP)
Good health and well-being
Openalex Percentile: Top 41%
Acute Kidney Injury Research
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