Vericiguat as a Novel Ferroptosis Inhibitor Alleviates Doxorubicin‐Induced Cardiotoxicity

These findings indicate that vericiguat protects against doxorubicin-induced myocardial ferroptosis, positioning it as a promising therapeutic candidate for DIC and a novel ferroptosis inhibitor.

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Publication Details

Journal
Basic & Clinical Pharmacology & Toxicology
Published
2026-03-05
DOI
https://doi.org/10.1111/bcpt.70219
Primary Topic
Ferroptosis and cancer prognosis
Type
article
Field-Weighted Citation Impact
0.00
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article

Vericiguat as a Novel Ferroptosis Inhibitor Alleviates Doxorubicin‐Induced Cardiotoxicity

Y. J. Wang, Haiqiong Liu, Y. Zhang, Zhiyin Zhang et al.
Basic & Clinical Pharmacology & Toxicology
Ferroptosis and cancer prognosis
article

Vericiguat as a Novel Ferroptosis Inhibitor Alleviates Doxorubicin‐Induced Cardiotoxicity

Y. J. Wang, Haiqiong Liu, Y. Zhang, Zhiyin Zhang, C X Liu, Tao Luo, Huan Han, Jiahao Wen, Shuwen Huang, Ziwei Zhang, Wen Ou, Xianbao Wang, Wenjun Luo
article en

Abstract

These findings indicate that vericiguat protects against doxorubicin-induced myocardial ferroptosis, positioning it as a promising therapeutic candidate for DIC and a novel ferroptosis inhibitor.

Basic & Clinical Pharmacology & ToxicologyVol. 138(4)
Zunyi Medical University (CN), University of California, Irvine (US), Fuwai Yunnan Cardiovascular Hospital (CN), Third Affiliated Hospital of Southern Medical University (CN), Guangzhou Development Zone Hospital (CN), Zhujiang Hospital (CN), Guangdong Provincial Center for Disease Control and Prevention (CN), Guangdong Provincial People's Hospital (CN), 421 Hospital of PLA (CN), Southern Medical University (CN)
Good health and well-being
Openalex Percentile: Top 32%
Ferroptosis and cancer prognosis
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