Role of Alpha-Synuclein in Frontotemporal Dementia: Narrative Review

α-Syn is a major, yet under-recognized, catalyst of neurodegeneration within the FTD spectrum. The findings emphasize the need for future therapeutic and diagnostic strategies to adopt multi-target approaches, addressing the synergistic toxicity of multiple protein aggregates rather than isolating single protein in isolation.

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Publication Details

Journal
Cells
Published
2026-03-05
DOI
https://doi.org/10.3390/cells15050470
Primary Topic
Parkinson's Disease Mechanisms and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Role of Alpha-Synuclein in Frontotemporal Dementia: Narrative Review

Anastasia Bougea
Cells
Parkinson's Disease Mechanisms and Treatments
article

Role of Alpha-Synuclein in Frontotemporal Dementia: Narrative Review

Anastasia Bougea
article en

Abstract

α-Syn is a major, yet under-recognized, catalyst of neurodegeneration within the FTD spectrum. The findings emphasize the need for future therapeutic and diagnostic strategies to adopt multi-target approaches, addressing the synergistic toxicity of multiple protein aggregates rather than isolating single protein in isolation.

CellsVol. 15(5)
National and Kapodistrian University of Athens (GR)
Good health and well-being
Openalex Percentile: Top 39%
Parkinson's Disease Mechanisms and Treatments
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