Functional and Survival Outcomes of Partial Versus Radical Nephrectomy in Renal Cell Carcinoma Patients With Pre-Existing Chronic Kidney Disease: A Real-World Study

PN is the preferred strategy for RCC patients with compromised renal function, when technically feasible, due to its superior functional outcomes. We propose a proteinuria-driven risk stratification approach; the presence of pre-operative proteinuria should strongly favor nephron-sparing surgery and necessitate rigorous long-term nephrological co-management to optimize survival.