Insulin-like growth factor 1 associated research in Alzheimer’s disease: an exploratory trends analysis

Research on IGF-1 and AD has continued to grow. Studies in this field have formed a tightly interconnected network, centered on the AD pathological core-IGF-1-related molecular mechanisms-downstream signaling pathways. The research focus is shifting from superficial correlations to investigations into underlying mechanisms and potential therapeutic targets. Depression and cognitive impairment are likely to become promising frontiers for future research.

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Publication Details

Journal
Frontiers in Neurology
Published
2026-03-05
DOI
https://doi.org/10.3389/fneur.2026.1709559
Primary Topic
Growth Hormone and Insulin-like Growth Factors
Type
article
Field-Weighted Citation Impact
0.00
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article

Insulin-like growth factor 1 associated research in Alzheimer’s disease: an exploratory trends analysis

Sheng-Qiang Zhou, Hui Yuan, Bo Li, Qin-Quan Zhu et al.
Frontiers in Neurology
Growth Hormone and Insulin-like Growth Factors
article

Insulin-like growth factor 1 associated research in Alzheimer’s disease: an exploratory trends analysis

Sheng-Qiang Zhou, Hui Yuan, Bo Li, Qin-Quan Zhu, Ming-Rong Xie, Yan-Jun Chen
article en

Abstract

Research on IGF-1 and AD has continued to grow. Studies in this field have formed a tightly interconnected network, centered on the AD pathological core-IGF-1-related molecular mechanisms-downstream signaling pathways. The research focus is shifting from superficial correlations to investigations into underlying mechanisms and potential therapeutic targets. Depression and cognitive impairment are likely to become promising frontiers for future research.

Frontiers in NeurologyVol. 17
Nanjing University of Chinese Medicine (CN), Hunan University (CN), Hunan Normal University (CN), First Affiliated Hospital of Hunan University of Traditional Chinese Medicine (CN), Hunan Academy of Traditional Chinese Medicine (CN), Affiliated Hospital of Liaoning University of Traditional Chinese Medicine (CN)
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Growth Hormone and Insulin-like Growth Factors
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