Cost-effectiveness of implantable cardioverter-defibrillators for primary prevention in heart failure with reduced ejection fraction: a Markov model using JROAD-DPC cost data in Japan
In the Japanese healthcare context, ICD implantation for primary prevention was found to be more cost-effective than the reference value. However, depending on several assumptions, the ICER may exceed the reference value. Sensitivity analyses highlighted the significant impact of the hazard ratio and battery longevity on cost-effectiveness. Further research is needed to identify subpopulations with significantly different cost-effectiveness outcomes.
Authors
- Hisashi Yokoshiki (ORCID: https://orcid.org/0000-0002-6247-2148)
- Teiichi Yamane
- Masahiko Takagi (ORCID: https://orcid.org/0000-0001-7712-8529)
- Yasuhiro Morii (ORCID: https://orcid.org/0000-0003-1392-3229)
- Katsuhiko Imai (ORCID: https://orcid.org/0000-0002-8080-5698)
- Kazuki Ohashi
- Katsuhiko Ogasawara
- Kengo Kusano
- Masaya Watanabe
- Hiroshi Tada
Institutions
- University of Fukui (JP)
- Hiroshima University (JP)
- Jikei University School of Medicine (JP)
- Kansai Medical University (JP)
- Health Sciences University of Hokkaido (JP)
- Hokkaido University (JP)
- Muroran Institute of Technology (JP)
- National Cerebral and Cardiovascular Center (JP)
- National Institute of Public Health (LA)
- Texas Cardiac Arrhythmia (US)
- Sapporo City General Hospital (JP)
- Kure Medical Center (JP)
- Memorial Hospital (US)
Publication Details
- Journal
- Frontiers in Cardiovascular Medicine
- Published
- 2026-03-05
- DOI
- https://doi.org/10.3389/fcvm.2026.1744517
- Primary Topic
- Cardiac pacing and defibrillation studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00