Salvianolic acid B attenuates cellular senescence and age-related decline in muscle function via dual mTOR/TP53INP2-autophagy regulation
The study demonstrates that SAB exerts beneficial effects on cellular aging markers, including SASP, ROS, and ATP levels, and alleviates age-related decline in muscle function.
Authors
- Kaixin Liang (ORCID: https://orcid.org/0000-0003-2916-9232)
- Hejing Zhao
- Yuanlong Ge
- Cheng Peng (ORCID: https://orcid.org/0000-0002-8558-496X)
- Zhenyu Ju
- Shu Wu
- Ruikun He
- Hansen Chen
- Mengying Hu
- Yihan Zhang
- Waner Xu
Institutions
- Laboratoire de Chémo-biologie synthétique et thérapeutique (FR)
- Guangzhou First People's Hospital (CN)
- Regenerative Medicine Institute (MX)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Frontiers in Chemistry
- Published
- 2026-03-05
- DOI
- https://doi.org/10.3389/fchem.2026.1771968
- Primary Topic
- Telomeres, Telomerase, and Senescence
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China