Oncological and Reproductive Outcomes of a Standardized Hysteroscopic Approach for the Fertility-Sparing Treatment of Atypical Endometrial Hyperplasia and Early-Stage Endometrial Cancer

A standardized hysteroscopic fertility-sparing approach combined with progestin therapy provides excellent oncologic control and favorable reproductive outcomes. Lesion severity did not affect outcomes when hysteroscopic removal was adequately performed, while patient age remains a key determinant of outcomes.

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Publication Details

Journal
Cancers
Published
2026-03-05
DOI
https://doi.org/10.3390/cancers18050839
Primary Topic
Gynecological conditions and treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Oncological and Reproductive Outcomes of a Standardized Hysteroscopic Approach for the Fertility-Sparing Treatment of Atypical Endometrial Hyperplasia and Early-Stage Endometrial Cancer

Eleonora La Fera, Francesca De Bonis, Michela Zorzi, Emma Bonetti et al.
Cancers
Gynecological conditions and treatments
article

Oncological and Reproductive Outcomes of a Standardized Hysteroscopic Approach for the Fertility-Sparing Treatment of Atypical Endometrial Hyperplasia and Early-Stage Endometrial Cancer

Eleonora La Fera, Francesca De Bonis, Michela Zorzi, Emma Bonetti, Ursula Catena, Giacomo Corrado, Valeria Masciullo, Giorgia Dinoi, Francesco Fanfani, Giulia Micol Bruni, Anna Fagotti
article en

Abstract

A standardized hysteroscopic fertility-sparing approach combined with progestin therapy provides excellent oncologic control and favorable reproductive outcomes. Lesion severity did not affect outcomes when hysteroscopic removal was adequately performed, while patient age remains a key determinant of outcomes.

CancersVol. 18(5)
Università Cattolica del Sacro Cuore (IT), University of Padua (IT), Agostino Gemelli University Polyclinic (IT), Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia (IT), Nuovo Ospedale San Giovanni di Dio (IT), University of Brescia (IT)
Good health and well-being
Openalex Percentile: Top 31%
Gynecological conditions and treatments
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