Italian guidelines for the use of digital breast tomosynthesis in breast cancer screening programmes: GRADE-ADOLOPMENT of the European guidelines

To enhance the quality of organized mammographic screening in Italy, in accordance with national legislation, a multidisciplinary panel of experts applied the Grading of Recommendations, Assessment, Development and Evaluation (GRADE)-ADOLOPMENT approach to adopt or adapt the European Commission Initiative on Breast Cancer (ECIBC) guidelines concerning the use of digital breast tomosynthesis (DBT). As prerequisite conditions for DBT adoption, the panel defines a full extension to women in the 45-74 age range, sufficient technical and professional resources, and an adequate monitoring system. The panel recommends the use of either DBT or digital mammography (DM) for asymptomatic women participating in organized screening programmes. However, it suggests prioritizing DBT in women with high mammographic breast density(classified as BI-RADS class c or d) when density has been previously assessed with DM. In the case of limited resources, priority in the implementation should be given to women with extremely dense breasts (BI-RADS class d). The use of DBT as an additional screening tool alongside DM is not recommended. These guidelines aim to provide a tailored approach for screening women with high mammographic breast density, improving detection while optimizing resource allocation in the context of organized screening. However, these recommendations also apply to the setting of spontaneous screening.

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Publication Details

Journal
La radiologia medica
Published
2026-03-05
DOI
https://doi.org/10.1007/s11547-026-02186-0
Primary Topic
Digital Radiography and Breast Imaging
Type
article
Field-Weighted Citation Impact
0.00

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article

Italian guidelines for the use of digital breast tomosynthesis in breast cancer screening programmes: GRADE-ADOLOPMENT of the European guidelines

Paola Golinelli, Carlo Senore, Flori Degrassi, Matteo Capobussi et al.
La radiologia medica
Digital Radiography and Breast Imaging
article

Italian guidelines for the use of digital breast tomosynthesis in breast cancer screening programmes: GRADE-ADOLOPMENT of the European guidelines

Paola Golinelli, Carlo Senore, Flori Degrassi, Matteo Capobussi, Francesca Caumo, Catia Angiolini, Livia Giordano, Vittorio Cannatà, Stella Pedilarco, Paola Bellardini, Antonella Pellegrini, Stefano Campa, Silvia Deandrea, Gian Paolo Morgano, Francesco Venturelli, Cristian Scatena, Margherita Serra, Leopoldo Costarelli, Marco Antonio Zappa, Adriana Bonifacino, Francesca Pietribiasi, Riccardo Vecchio, Alfonso Frigerio, Giulio Francolini, Carlo Magliocca, Elisa Betti, Massimo Calabrese, Mario Taffurelli, Francesco Sardanelli, Lauro Bucchi, Stefania Montemezzi, Prassede Foxi, Gioele Santucci, Isabella Castellano, Andrea Guida, Icro Meattini, Valeria Fava, Annalisa Trianni, Martina Rossi, Marco Moschetta, Paola Mosconi, Alfredo Santinelli, Marzia Salgarello, Gabriella Dardanoni, Stefano Pacifici, Priscilla Sassoli de’ Bianchi, Eugenio Paci, Marco Rosselli del Turco, Eva Carnesciali, Luigi Bisanti, Stefania Gori, Loredana Pau, Daniela Ambrogetti, Emanuele Torri, Francesca Battisti, Roberto Satolli, Paolo Giorgi Rossi
article en

Abstract

To enhance the quality of organized mammographic screening in Italy, in accordance with national legislation, a multidisciplinary panel of experts applied the Grading of Recommendations, Assessment, Development and Evaluation (GRADE)-ADOLOPMENT approach to adopt or adapt the European Commission Initiative on Breast Cancer (ECIBC) guidelines concerning the use of digital breast tomosynthesis (DBT). As prerequisite conditions for DBT adoption, the panel defines a full extension to women in the 45-74 age range, sufficient technical and professional resources, and an adequate monitoring system. The panel recommends the use of either DBT or digital mammography (DM) for asymptomatic women participating in organized screening programmes. However, it suggests prioritizing DBT in women with high mammographic breast density(classified as BI-RADS class c or d) when density has been previously assessed with DM. In the case of limited resources, priority in the implementation should be given to women with extremely dense breasts (BI-RADS class d). The use of DBT as an additional screening tool alongside DM is not recommended. These guidelines aim to provide a tailored approach for screening women with high mammographic breast density, improving detection while optimizing resource allocation in the context of organized screening. However, these recommendations also apply to the setting of spontaneous screening.

La radiologia medica
Fondazione Roma (IT), Ministero della Salute (IT), Azienda Ospedaliera Citta' della Salute e della Scienza di Torino (IT), Azienda Sanitaria Unità Locale di Reggio Emilia (IT), Istituti Clinici Scientifici Maugeri (IT), Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IT), Istituto Oncologico Veneto (IT), Agenzia Sanitaria e Sociale Regionale (IT), Joint Research Centre (IT), ANT Foundation Italy Onlus (IT), League Against Cancer (US), Lega Italiana per la Lotta ai Tumori (IT), Ospedale Policlinico San Martino (IT), Istituti di Ricovero e Cura a Carattere Scientifico (IT), Azienda Usl Toscana Centro (IT), Regione Lombardia, Regione Emilia-Romagna
Regione Emilia-Romagna
Openalex Percentile: Top 32%
Digital Radiography and Breast Imaging
DOIOpen Access PDFOpenAlex
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