Critical role of Sirtuin 6 (SIRT6) in osteoarthritis chondrocytes: the interaction among various biological processes
This review describes the multi-faceted protective roles of SIRT6 in OA chondrocytes. SIRT6 participates in many biological processes and acts as a key node interacting with many cytokines to regulate OA progression. With further researches, the mechanisms of it will be more explicit and it might be a potential therapeutic target for OA treatment.
Authors
- Zongru He
- Ning Ding (ORCID: https://orcid.org/0000-0003-3141-2852)
- Qingshan Yang
Institutions
- Gansu Provincial Hospital (CN)
Publication Details
- Journal
- Annals of Medicine
- Published
- 2026-03-05
- DOI
- https://doi.org/10.1080/07853890.2026.2638000
- Primary Topic
- Sirtuins and Resveratrol in Medicine
- Type
- article
- Field-Weighted Citation Impact
- 0.00