Association of Glymphatic Dysfunction with Cognitive Performance in Type 2 Diabetes Mellitus and Prediabetes

PDM and T2DM exhibit GS alterations, including reduced DTI-ALPS index and increased CP volume and FW index, which are associated with poorer cognition. GS metrics may serve as potential neuroimaging biomarkers for cognitive impairment in this population.

Authors

Publication Details

Journal
Neuroendocrinology
Published
2026-03-05
DOI
https://doi.org/10.1159/000551127
Primary Topic
Cerebrospinal fluid and hydrocephalus
Type
article
Field-Weighted Citation Impact
0.00

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Association of Glymphatic Dysfunction with Cognitive Performance in Type 2 Diabetes Mellitus and Prediabetes

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Association of Glymphatic Dysfunction with Cognitive Performance in Type 2 Diabetes Mellitus and Prediabetes

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article en

Abstract

PDM and T2DM exhibit GS alterations, including reduced DTI-ALPS index and increased CP volume and FW index, which are associated with poorer cognition. GS metrics may serve as potential neuroimaging biomarkers for cognitive impairment in this population.

Neuroendocrinology
National Natural Science Foundation of China, Southern Medical University, Nanfang Hospital
No poverty
Openalex Percentile: Top 33%
Cerebrospinal fluid and hydrocephalus
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