Profiles of neuropsychiatric toxicity associated with different endocrine therapies for breast cancer: a global pharmacovigilance study based on FAERS and VigiAccess
This study conducted a comprehensive pharmacovigilance assessment of neurotoxicity and psychiatric events in endocrine therapy for breast cancer. The findings indicated heterogeneous patterns of neuropsychiatric safety signals and reporting burdens across drug classes, offering new insights relevant to clinical monitoring practices.
Authors
- Ge Li (ORCID: https://orcid.org/0000-0002-2564-7076)
- Mengqi Yang (ORCID: https://orcid.org/0000-0002-9959-6339)
- Yajie Liu (ORCID: https://orcid.org/0000-0002-6581-5062)
- Lei Zhang (ORCID: https://orcid.org/0009-0008-9783-092X)
- Xin Li
- Feng Peng
- Xiaoliang Wu
Institutions
- Peking University Shenzhen Hospital (CN)
- University of Hong Kong - Shenzhen Hospital (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2026-03-05
- DOI
- https://doi.org/10.3389/fphar.2026.1731849
- Primary Topic
- Cancer-related cognitive impairment studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- World Health Organization
- Peking University