Augmented CENH3 loading is accompanied by transcriptional and epigenetic reprogramming at rice centromeres during meiosis
Our findings uncover a previously unrecognized, meiotic-specific pattern of CENH3 loading in rice and highlight a coordinated regulatory network linking centromeric chromatin reorganization, transcriptional repression, and epigenetic modification during early meiotic progression.
Authors
- Lei Cao (ORCID: https://orcid.org/0000-0002-0755-6488)
- Zhukuan Cheng (ORCID: https://orcid.org/0000-0001-8428-8010)
- Yonghang Run
- Yangzi Zhao (ORCID: https://orcid.org/0000-0003-2077-6319)
- Minsi Wen
- Wenli Zhang (ORCID: https://orcid.org/0000-0001-9077-4189)
- Y. R. Shen (ORCID: https://orcid.org/0000-0001-8023-2765)
- Yafei Li (ORCID: https://orcid.org/0000-0002-0010-5940)
- Bingxin Wang
- Jiawei Chen
- Hanli You
- Huixin Liu
- Han Yang
- Pengtao Zhao
Institutions
- Nanjing Agricultural University (CN)
- Huaibei Normal University (CN)
- Chinese Academy of Sciences (CN)
- Institute of Genetics and Developmental Biology (CN)
- University of Chinese Academy of Sciences (CN)
- Yangzhou University (CN)
Publication Details
- Journal
- Genome biology
- Published
- 2026-03-05
- DOI
- https://doi.org/10.1186/s13059-026-04020-2
- Primary Topic
- Chromosomal and Genetic Variations
- Type
- article
- Field-Weighted Citation Impact
- 0.00