Ethanol Extracts of <i>Justicia carnea</i> Leaves Mitigate Pancreatic Oxidative Stress and Preserve Islet Glucagon Expression in TNBS-treated Mice

Chronic pancreatitis is an inflammatory disease and is difficult to manage despite advancements in medical science. This study examined the effect of water/ethanol extracts of Justicia carnea leaves on oxidative stress and glucagon expression in a mouse model of chronic pancreatitis induced by trinitrobenzenesulfonic acid (TNBS).

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Publication Details

Journal
Journal of Exploratory Research in Pharmacology
Published
2026-03-05
DOI
https://doi.org/10.14218/jerp.2025.00044
Primary Topic
Natural Antidiabetic Agents Studies
Type
article
Field-Weighted Citation Impact
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article

Ethanol Extracts of Justicia carnea Leaves Mitigate Pancreatic Oxidative Stress and Preserve Islet Glucagon Expression in TNBS-treated Mice

Osuvwe C. Orororo, Mamerhi Taniyohwo Enaohwo, Othuke Bensandy Odeghe, Kingsley Chinedu Enyi et al.
Journal of Exploratory Research in Pharmacology
Natural Antidiabetic Agents Studies
article

Ethanol Extracts of Justicia carnea Leaves Mitigate Pancreatic Oxidative Stress and Preserve Islet Glucagon Expression in TNBS-treated Mice

Osuvwe C. Orororo, Mamerhi Taniyohwo Enaohwo, Othuke Bensandy Odeghe, Kingsley Chinedu Enyi, Chukwudi Cyril Dunkwu, Joan Mode, Jennifer Efe Jaiyeoba-Ojigho
article en

Abstract

Chronic pancreatitis is an inflammatory disease and is difficult to manage despite advancements in medical science. This study examined the effect of water/ethanol extracts of Justicia carnea leaves on oxidative stress and glucagon expression in a mouse model of chronic pancreatitis induced by trinitrobenzenesulfonic acid (TNBS).

Journal of Exploratory Research in PharmacologyVol. 11(1)
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Openalex Percentile: Top 34%
Natural Antidiabetic Agents Studies
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