Protective Properties of Carboxychromanate-2-ethyl-6-methyl-3-hydroxypyridine, Caused by Its Antiradical Properties

The antiradical properties and biological activity of Carboxychromanate 2-ethyl-6-methyl-3-hydroxypyridine (ChHP) were studied. The preparation had high antiradical activity. At concentrations of 10–6 and 10–9 M, carboxychromanate 2-ethyl-6-methyl-3-hydroxypyridine prevented the activation of lipid peroxidation in the membranes of pea seedlings mitochondria incubated in a hypotonic medium, which probably indicated the presence of antistress properties. These properties were studied under conditions of water deficiency, causing lipid peroxidation. Treatment of pea seeds with 10–9 M drug prevented the activation of lipid peroxidation in mitochondrial membranes and a decrease in the growth rate of pea seedlings under conditions of water deficiency. It is assumed that the studied preparation is a plant growth regulator.

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Publication Details

Journal
Russian Journal of Physical Chemistry B
Published
2026-02-24
DOI
https://doi.org/10.1134/s1990793125701581
Primary Topic
Free Radicals and Antioxidants
Type
article
Field-Weighted Citation Impact
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article

Protective Properties of Carboxychromanate-2-ethyl-6-methyl-3-hydroxypyridine, Caused by Its Antiradical Properties

Yu. V. Kuznetsov, I. V. Zhigacheva, N. I. Krikunova, T. L. Veprintsev et al.
Russian Journal of Physical Chemistry B
Free Radicals and Antioxidants
article

Protective Properties of Carboxychromanate-2-ethyl-6-methyl-3-hydroxypyridine, Caused by Its Antiradical Properties

Yu. V. Kuznetsov, I. V. Zhigacheva, N. I. Krikunova, T. L. Veprintsev, I. F. Rusina
article en

Abstract

The antiradical properties and biological activity of Carboxychromanate 2-ethyl-6-methyl-3-hydroxypyridine (ChHP) were studied. The preparation had high antiradical activity. At concentrations of 10–6 and 10–9 M, carboxychromanate 2-ethyl-6-methyl-3-hydroxypyridine prevented the activation of lipid peroxidation in the membranes of pea seedlings mitochondria incubated in a hypotonic medium, which probably indicated the presence of antistress properties. These properties were studied under conditions of water deficiency, causing lipid peroxidation. Treatment of pea seeds with 10–9 M drug prevented the activation of lipid peroxidation in mitochondrial membranes and a decrease in the growth rate of pea seedlings under conditions of water deficiency. It is assumed that the studied preparation is a plant growth regulator.

Russian Journal of Physical Chemistry B
Semenov Institute of Chemical Physics (RU), Institute of Biochemical Physics NM Emanuel (RU)
Openalex Percentile: Top 33%
Free Radicals and Antioxidants
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