Aficamten in symptomatic obstructive hypertrophic cardiomyopathy: the FOREST-HCM long-term study
Extended aficamten treatment in patients with symptomatic oHCM yielded early and sustained hemodynamic and clinical responses with low incidences of new-onset atrial fibrillation and LVEF<50%.
Authors
- Tyrell Simkins (ORCID: https://orcid.org/0000-0002-6063-174X)
- Jenny Wei (ORCID: https://orcid.org/0009-0000-5828-5705)
- Albree Tower‐Rader
- Ahmad Munir Masri
- Michael E. Nassif (ORCID: https://orcid.org/0000-0002-1232-7604)
- Xueli Liu (ORCID: https://orcid.org/0000-0001-8692-1078)
- Fady I. Malik
- Roberto Barriales-Villa
- Artur Oreziak
- Sara Saberi
- S B Heitner
- S Kupfer
- I Olivotto
- R M Cooper
- C Melloni
- T Abraham
- Perry M Elliott
- Scott D Solomon
- Anjali Tiku Owens
- Martin S Maron
Institutions
- Northwestern University (US)
- Brigham and Women's Hospital (US)
- Lahey Hospital and Medical Center (US)
- Saint Luke's Health System (US)
- Harvard University (US)
- Oregon Health & Science University (US)
- Queen Mary University of London (GB)
- University of California, San Francisco (US)
- University of Michigan (US)
- British Heart Foundation (GB)
- Massachusetts General Hospital (US)
- Lahey Medical Center (US)
- Michigan Medicine (US)
- Centro de Investigación Biomédica en Red (ES)
- The Arrhythmia Institute (US)
- Saint Luke's Hospital (US)
- Cytokinetics (United States) (US)
- Complexo Hospitalario Universitario A Coruña (ES)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- Instituto de Investigación Biomédica de A Coruña (ES)
- University College London (GB)
- Liverpool John Moores University (GB)
- University of Pennsylvania (US)
Publication Details
- Journal
- European Heart Journal
- Published
- 2025-12-24
- DOI
- https://doi.org/10.1093/eurheartj/ehaf1085
- Citations
- 1
- Primary Topic
- Cardiomyopathy and Myosin Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.39