Efficacy and safety of Cortexin as additional therapy in patients with depressive disorder

The use of Cortexin as an additional therapy in patients with depressive disorder is effective and safe. Combined antidepressant therapy with Cortexin is superior to antidepressant monotherapy in terms of response rate and health-related quality of life. A more favorable safety profile was also demonstrated for the combination of antidepressants and Cortexin.

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Publication Details

Journal
S S Korsakov Journal of Neurology and Psychiatry
Published
2026-03-05
DOI
https://doi.org/10.17116/jnevro202612602192
Primary Topic
Treatment of Major Depression
Type
article
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0.00
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article

Efficacy and safety of Cortexin as additional therapy in patients with depressive disorder

ED Schastnyy
S S Korsakov Journal of Neurology and Psychiatry
Treatment of Major Depression
article

Efficacy and safety of Cortexin as additional therapy in patients with depressive disorder

ED Schastnyy
article en

Abstract

The use of Cortexin as an additional therapy in patients with depressive disorder is effective and safe. Combined antidepressant therapy with Cortexin is superior to antidepressant monotherapy in terms of response rate and health-related quality of life. A more favorable safety profile was also demonstrated for the combination of antidepressants and Cortexin.

S S Korsakov Journal of Neurology and PsychiatryVol. 126(2)
Mental Health Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences (RU), Tomsk National Research Medical Center (RU)
Good health and well-being
Openalex Percentile: Top 33%
Treatment of Major Depression
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