The intersection of disorders of sex development and cardiovascular diseases

Our findings suggest a genetic link between 46 XY DSD and CVD, indicating that shared molecular mechanisms may play a role in the development of both conditions. These insights into the connections could have important implications for personalized medicine, potentially allowing for treatments that target both 46 XY DSD and CVD.

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Publication Details

Journal
Biology of Sex Differences
Published
2026-03-05
DOI
https://doi.org/10.1186/s13293-025-00814-4
Primary Topic
Sexual Differentiation and Disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

The intersection of disorders of sex development and cardiovascular diseases

Rédouane Aherrahrou, Satwat Hashmi
Biology of Sex Differences
Sexual Differentiation and Disorders
article

The intersection of disorders of sex development and cardiovascular diseases

Rédouane Aherrahrou, Satwat Hashmi
article en

Abstract

Our findings suggest a genetic link between 46 XY DSD and CVD, indicating that shared molecular mechanisms may play a role in the development of both conditions. These insights into the connections could have important implications for personalized medicine, potentially allowing for treatments that target both 46 XY DSD and CVD.

Biology of Sex Differences
Aga Khan University (PK), University of Eastern Finland (FI), Augusta University (US), German Centre for Cardiovascular Research (DE), University of Lübeck (DE)
Good health and well-being
Openalex Percentile: Top 33%
Sexual Differentiation and Disorders
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