Preparation and Immunogenicity Prediction of Brucella melitensis mRNA Vaccine Candidate Based on omp16 and omp19 Genes

The immunogenic proteins were successfully expressed in cells based on the mRNA fragments synthesized from <i>omp16</i> and <i>omp19</i> genes of <i>B. melitensis</i>, which was a preliminary exploration for the preparation of <i>B. melitensis</i> mRNA vaccine.

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Publication Details

Journal
Vaccines
Published
2026-03-05
DOI
https://doi.org/10.3390/vaccines14030240
Primary Topic
Brucella: diagnosis, epidemiology, treatment
Type
article
Field-Weighted Citation Impact
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article

Preparation and Immunogenicity Prediction of Brucella melitensis mRNA Vaccine Candidate Based on omp16 and omp19 Genes

Huricha Baigude, Haiyan Borijihan, Fu Quan, Jingjie Zhang et al.
Vaccines
Brucella: diagnosis, epidemiology, treatment
article

Preparation and Immunogenicity Prediction of Brucella melitensis mRNA Vaccine Candidate Based on omp16 and omp19 Genes

Huricha Baigude, Haiyan Borijihan, Fu Quan, Jingjie Zhang, Lili Bao, Yixuan Chen, Dezhi Yang
article en

Abstract

The immunogenic proteins were successfully expressed in cells based on the mRNA fragments synthesized from <i>omp16</i> and <i>omp19</i> genes of <i>B. melitensis</i>, which was a preliminary exploration for the preparation of <i>B. melitensis</i> mRNA vaccine.

VaccinesVol. 14(3)
Inner Mongolia University (CN), Inner Mongolia International Mongolian Hospital (CN), Inner Mongolia Medical University (CN)
Good health and well-being
Openalex Percentile: Top 33%
Brucella: diagnosis, epidemiology, treatment
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