Nowarta110 Displays Antiviral Properties Against Coxsackievirus B and Herpes Simplex Virus 2

Nowarta110 is a novel fig extract and colloidal silver therapeutic composition initially designed to treat plantar warts caused by human papilloma virus (HPV). In a recent study, we also demonstrated that our nutraceutical formulation exhibits potent antitumoral activity in mice xenografted with HPV-transformed cells. Fig extracts have been shown to provide antiviral effects toward a number of viruses; thus, to explore Nowarta110's potential antiviral activity, we evaluated its impact on <i>in vitro</i> models of both Coxsackievirus B (CVB) and herpes simplex virus type 2 infections. We found that Nowarta110 significantly reduced infection of human cells with both CVB and herpes simplex virus 2. In all, these findings demonstrate that Nowarta110 possesses antiviral properties against a broad range of viruses. Thus, further studies interrogating its antiviral therapeutic potential are warranted.

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Publication Details

Journal
Journal of Medicinal Food
Published
2026-03-04
DOI
https://doi.org/10.1177/1096620x261427691
Primary Topic
Phytochemistry and biological activities of Ficus species
Type
article
Field-Weighted Citation Impact
0.00
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article

Nowarta110 Displays Antiviral Properties Against Coxsackievirus B and Herpes Simplex Virus 2

Ba X. Hoang, Jon Sin, Hai T. Tran, FERRE AKBARPOUR et al.
Journal of Medicinal Food
Phytochemistry and biological activities of Ficus species
article

Nowarta110 Displays Antiviral Properties Against Coxsackievirus B and Herpes Simplex Virus 2

Ba X. Hoang, Jon Sin, Hai T. Tran, FERRE AKBARPOUR, Anh Tuấn Nguyễn, Bo Han, Thanh X Hoang
article en

Abstract

Nowarta110 is a novel fig extract and colloidal silver therapeutic composition initially designed to treat plantar warts caused by human papilloma virus (HPV). In a recent study, we also demonstrated that our nutraceutical formulation exhibits potent antitumoral activity in mice xenografted with HPV-transformed cells. Fig extracts have been shown to provide antiviral effects toward a number of viruses; thus, to explore Nowarta110's potential antiviral activity, we evaluated its impact on <i>in vitro</i> models of both Coxsackievirus B (CVB) and herpes simplex virus type 2 infections. We found that Nowarta110 significantly reduced infection of human cells with both CVB and herpes simplex virus 2. In all, these findings demonstrate that Nowarta110 possesses antiviral properties against a broad range of viruses. Thus, further studies interrogating its antiviral therapeutic potential are warranted.

Journal of Medicinal Food
University of Southern California (US), Orange County School (US), Medical Research Foundation (GB)
Openalex Percentile: Top 35%
Phytochemistry and biological activities of Ficus species
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