MycoMobilome: a community-focused non-redundant database of transposable element consensus sequences for the fungal kingdom

Transposable elements (TEs) are found in nearly all eukaryotic genomes. Despite significant advances in the sequencing of genomes, TE resources remain sparse, leading to a lack of traceability, reproducibility, and duplication of effort when annotating TEs. Here, we focus on the fungal kingdom and present MycoMobilome, a database of TE consensus sequences computationally curated using a set of 4309 genomes covering all major clades. The initial database contains 586 441 consensus sequences after filtering to remove putative host genes and low-quality consensus sequences. We provide a consistent naming convention to surface information on the confidence in the classification, including potential conflicting open reading frame functions, along with metadata to enable evaluation of TEs of interest and to determine whether further curation work is required on a case-by-case basis. Finally, we provide guidelines for community contributions and encourage researchers to deposit new or curated sequences, which will be incorporated into future MycoMobilome releases.

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Publication Details

Journal
NAR Genomics and Bioinformatics
Published
2026-01-06
DOI
https://doi.org/10.1093/nargab/lqag026
Primary Topic
Chromosomal and Genetic Variations
Type
article
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article

MycoMobilome: a community-focused non-redundant database of transposable element consensus sequences for the fungal kingdom

Tobias Baril, Daniel Croll
NAR Genomics and Bioinformatics
Chromosomal and Genetic Variations
article

MycoMobilome: a community-focused non-redundant database of transposable element consensus sequences for the fungal kingdom

Tobias Baril, Daniel Croll
article en

Abstract

Transposable elements (TEs) are found in nearly all eukaryotic genomes. Despite significant advances in the sequencing of genomes, TE resources remain sparse, leading to a lack of traceability, reproducibility, and duplication of effort when annotating TEs. Here, we focus on the fungal kingdom and present MycoMobilome, a database of TE consensus sequences computationally curated using a set of 4309 genomes covering all major clades. The initial database contains 586 441 consensus sequences after filtering to remove putative host genes and low-quality consensus sequences. We provide a consistent naming convention to surface information on the confidence in the classification, including potential conflicting open reading frame functions, along with metadata to enable evaluation of TEs of interest and to determine whether further curation work is required on a case-by-case basis. Finally, we provide guidelines for community contributions and encourage researchers to deposit new or curated sequences, which will be incorporated into future MycoMobilome releases.

NAR Genomics and BioinformaticsVol. 8(1)
University of Neuchâtel (CH)
Quality Education
Openalex Percentile: Top 35%
Chromosomal and Genetic Variations
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