Familial Occurrence of Type 1 Diabetes Mellitus in Korean Children and Adolescents: A Multicenter Study

In this multicenter Korean cohort, familial T1DM accounted for 3.4% of pediatric cases, which was lower than in Western populations. Subsequent-affected children exhibited milder metabolic decompensation at diagnosis than did index children, likely reflecting earlier recognition through family awareness and screening. These findings underscore the importance of early education and monitoring of at-risk relatives within affected families.

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Publication Details

Journal
Diabetes & Metabolism Journal
Published
2026-03-05
DOI
https://doi.org/10.4093/dmj.2025.1149
Primary Topic
Diabetes and associated disorders
Type
article
Field-Weighted Citation Impact
0.00

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article

Familial Occurrence of Type 1 Diabetes Mellitus in Korean Children and Adolescents: A Multicenter Study

Aram Yang, Myung Ji Yoo, SUJIN KIM, Moon Bae AHN et al.
Diabetes & Metabolism Journal
Diabetes and associated disorders
article

Familial Occurrence of Type 1 Diabetes Mellitus in Korean Children and Adolescents: A Multicenter Study

Aram Yang, Myung Ji Yoo, SUJIN KIM, Moon Bae AHN, J. T. Kim, Hyun Wook Chae, Young‐Lim Shin, Insung Kim, Hwa Young Kim, Hae Sang Lee, Su Jin Park, Eungu Kang, Sung Yoon Cho, C. S. Kim, Kyungmi Jang, Mo Kyung Jung, Han Sol Kim, Soo Yeun Sim, Mi Yang, Jisun Park, Eun Young Joo, Junghwan Suh, Hyo-Kyoung Nam, Yoo-Mi Kim, Jung Eun Moon, Jieun Lee, Young-Jun Rhie, Han Hyuk Lim, Minsun Kim, Min Hyung Cho, Seo Jung Kim, Yong Hee Hong, Yong Hyuk Kim, Su Jin Kim, Kyungchul Song, Minji Im, Yun Jeong Kim, Yoonha Lee
article en

Abstract

In this multicenter Korean cohort, familial T1DM accounted for 3.4% of pediatric cases, which was lower than in Western populations. Subsequent-affected children exhibited milder metabolic decompensation at diagnosis than did index children, likely reflecting earlier recognition through family awareness and screening. These findings underscore the importance of early education and monitoring of at-risk relatives within affected families.

Diabetes & Metabolism Journal
Yonsei University (KR), Chungnam National University (KR), Korea University (KR), Soonchunhyang University (KR), Severance Hospital (KR), Korea University Medical Center (KR), Kyungpook National University Hospital (KR), Samsung Medical Center (KR), Seoul National University Bundang Hospital (KR), Chonnam National University Hospital (KR), Wonju Severance Christian Hospital (KR), Ajou University Hospital (KR), Kangbuk Samsung Hospital (KR), CHA University Bundang Medical Center (KR), Chungnam National University Hospital (KR), Gangnam Severance Hospital (KR), CHA University (KR), Inha University Hospital (KR), The Catholic University of Korea Seoul St. Mary's Hospital (KR), Ajou University (KR), Bucheon University (KR), Jeonbuk National University (KR), Sungkyunkwan University (KR), Catholic University of Korea (KR)
National Institutes of Health
Openalex Percentile: Top 34%
Diabetes and associated disorders
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