An exploratory study of altered regional homogeneity in Parkinson’s disease with depression

DPD is associated with distinct ReHo alterations. Abnormalities in the left ITG, right MFG, left insula, and left hippocampus may reflect the neural basis of DPD. Our exploratory analyses suggest that altered ReHo in the left insula and left hippocampus may hold potential as neuroimaging biomarkers.

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Publication Details

Journal
Frontiers in Psychiatry
Published
2026-03-05
DOI
https://doi.org/10.3389/fpsyt.2026.1771679
Primary Topic
Parkinson's Disease Mechanisms and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

An exploratory study of altered regional homogeneity in Parkinson’s disease with depression

Bo Li, Lei Chen, Xuetao Zhu, Rumeng Zhang et al.
Frontiers in Psychiatry
Parkinson's Disease Mechanisms and Treatments
article

An exploratory study of altered regional homogeneity in Parkinson’s disease with depression

Bo Li, Lei Chen, Xuetao Zhu, Rumeng Zhang, Chao Zhang, Shihua Liu, Yan Chen, Ping Zhong
article en

Abstract

DPD is associated with distinct ReHo alterations. Abnormalities in the left ITG, right MFG, left insula, and left hippocampus may reflect the neural basis of DPD. Our exploratory analyses suggest that altered ReHo in the left insula and left hippocampus may hold potential as neuroimaging biomarkers.

Frontiers in PsychiatryVol. 17
Anhui Medical University (CN)
Good health and well-being
Openalex Percentile: Top 39%
Parkinson's Disease Mechanisms and Treatments
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