VEGF‐Positive Mass‐Forming Intrahepatic Cholangiocarcinoma: New Subtype Based on Radiological and Molecular Pathological Analysis
H-ICC is characterized by hyperenhancement occupying ≥ 50% of the tumor area on dynamic CT, high AVD, and elevated VEGFA expression. These findings support a distinct clinicopathological subset identifiable by LAP enhancement and VEGF immunostaining.
Authors
- Shigeyoshi Soga (ORCID: https://orcid.org/0000-0002-1439-2282)
- Naoto Kubota
- Yasuhito Arai
- Masahiro Jinzaki
- Junya Tsuzaki
- Hidenori Ojima
- Tatsuhiro Shibata
Institutions
- Keio University (JP)
- Tochigi Cancer Center (JP)
- Dokkyo Medical University (JP)
Publication Details
- Journal
- Hepatology Research
- Published
- 2026-03-04
- DOI
- https://doi.org/10.1111/hepr.70151
- Primary Topic
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00