Neutrophil extracellular traps-associated candidate genes in IgA vasculitis: an exploratory multi-omics analysis integrating transcriptomics and Mendelian randomization
This exploratory multi-omics study identified a set of NET-associated candidate genes showing consistent associations with IgAV. These findings provide a hypothesis-generating framework for understanding NET-related immune processes in IgAV and warrant further validation in larger cohorts and functional studies.
Authors
- Liyu Lin
- Wen Luo (ORCID: https://orcid.org/0000-0002-3558-4136)
- Jiaqiang Wu (ORCID: https://orcid.org/0009-0002-8289-7853)
- Zilun Wu (ORCID: https://orcid.org/0009-0000-1136-2822)
Institutions
- Guangzhou University of Chinese Medicine (CN)
- First Affiliated Hospital of Guangzhou University of Chinese Medicine (CN)
Publication Details
- Journal
- Pediatric Rheumatology
- Published
- 2026-03-05
- DOI
- https://doi.org/10.1186/s12969-026-01197-5
- Primary Topic
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00