Impact of risperidone and voluntary exercise on ketone body metabolism-related gene expression in the brain of female juvenile rats
Risperidone may suppress the expression of key ketogenic enzymes, while exercise appears to exert a compensatory, stimulatory effect. Exercise may partially restore ketogenic gene expression in risperidone-treated animals. The results suggest a region-specific modulation of brain energy metabolism by both interventions.
Authors
- Weijie Yi (ORCID: https://orcid.org/0000-0002-4884-7732)
- Jiamei Lian
- Chao Deng
Institutions
- University of Wollongong (AU)
Publication Details
- Journal
- Behavioural Brain Research
- Published
- 2026-03-05
- DOI
- https://doi.org/10.1016/j.bbr.2026.116143
- Primary Topic
- Diet and metabolism studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00