Trends and disparities in bone cancer mortality among US adults from 1999 to 2020: a joinpoint regression analysis based on the CDC WONDER database

Bone cancer mortality among US adults showed an overall increasing trend from 1999 to 2020, with significant disparities by age, sex, race, and geographic region. The triphasic mortality trend may reflect evolving diagnostic technologies, treatment approaches, and healthcare accessibility. These findings provide valuable insights for public health planning and resource allocation aimed at reducing the burden of bone malignancies.

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Publication Details

Journal
Frontiers in Oncology
Published
2026-03-05
DOI
https://doi.org/10.3389/fonc.2026.1718354
Primary Topic
Management of metastatic bone disease
Type
article
Field-Weighted Citation Impact
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article

Trends and disparities in bone cancer mortality among US adults from 1999 to 2020: a joinpoint regression analysis based on the CDC WONDER database

Yinghu Deng, Lei Wei, Zhixiang Ma, Xiaosi Zhang
Frontiers in Oncology
Management of metastatic bone disease
article

Trends and disparities in bone cancer mortality among US adults from 1999 to 2020: a joinpoint regression analysis based on the CDC WONDER database

Yinghu Deng, Lei Wei, Zhixiang Ma, Xiaosi Zhang
article en

Abstract

Bone cancer mortality among US adults showed an overall increasing trend from 1999 to 2020, with significant disparities by age, sex, race, and geographic region. The triphasic mortality trend may reflect evolving diagnostic technologies, treatment approaches, and healthcare accessibility. These findings provide valuable insights for public health planning and resource allocation aimed at reducing the burden of bone malignancies.

Frontiers in OncologyVol. 16
The People's Hospital Tongling (CN)
Good health and well-being
Openalex Percentile: Top 33%
Management of metastatic bone disease
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