Cannabinoid Hyperemesis Syndrome-A Survey-Based Approach to Understanding Symptoms and Cannabis Use Patterns

Our findings suggest that CHS is most associated with long-term, frequent use of inhaled delta-9-tetrahydrocannabinol (Δ9-THC) dominant cannabis. The acquisition source of cannabis products did not affect the syndrome presentation. Although many different cannabis consumption methods were represented, smoking and vape cartridges were the most commonly reported. The use of vape cartridges was associated with a shorter time to the development of CHS symptoms. Increased awareness of these patterns could improve the early recognition and management of CHS.

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Publication Details

Journal
Cannabis and Cannabinoid Research
Published
2026-03-05
DOI
https://doi.org/10.1177/25785125261421434
Primary Topic
Cannabis and Cannabinoid Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Cannabinoid Hyperemesis Syndrome-A Survey-Based Approach to Understanding Symptoms and Cannabis Use Patterns

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Cannabis and Cannabinoid Research
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Cannabinoid Hyperemesis Syndrome-A Survey-Based Approach to Understanding Symptoms and Cannabis Use Patterns

Riley D. Kirk, Jill S. Simonian, Cecilia Peterson, Ariana M. Nelson, Ryan A. Lacinski, Megan Mbengue, Katie Nava, Jacqueline Higgins
article en

Abstract

Our findings suggest that CHS is most associated with long-term, frequent use of inhaled delta-9-tetrahydrocannabinol (Δ9-THC) dominant cannabis. The acquisition source of cannabis products did not affect the syndrome presentation. Although many different cannabis consumption methods were represented, smoking and vape cartridges were the most commonly reported. The use of vape cartridges was associated with a shorter time to the development of CHS symptoms. Increased awareness of these patterns could improve the early recognition and management of CHS.

Cannabis and Cannabinoid Research
West Virginia University (US), Santa Rosa Junior College (US), University of California, Irvine (US), University of California San Diego (US), Kindred Hospital Rancho (US), California Wellness Foundation (US), Irvine University (US), Patient Advocate Foundation (US)
Good health and well-being
Openalex Percentile: Top 33%
Cannabis and Cannabinoid Research
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