Diagnostic challenge of high vitamin B12 levels: a case report and review of the literature
High serum B12 levels may be due to a wide range of conditions, including severe diseases; when high levels of vitamin B12 are detected, it is useful to perform a screening for the most well-known conditions associated with this finding. The use of methods such as polyethylene glycole precipitation consent to identify the possible presence of a macro-B12.
Authors
- Giovanni Covini (ORCID: https://orcid.org/0000-0003-1632-3907)
- Alessandro Manca
- S. Badalamenti
- Marta Calatroni
- Renato Alberto Sinico
- Francesca Margherita Panvini
- Matteo Stella
- Francesco Reggiani
Institutions
- Humanitas University (IT)
- IRCCS Humanitas Research Hospital (IT)
Publication Details
- Journal
- Journal of Medical Case Reports
- Published
- 2026-03-05
- DOI
- https://doi.org/10.1186/s13256-026-05898-z
- Primary Topic
- Folate and B Vitamins Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00