The emergence of pan-drug-resistant Pseudomonas aeruginosa in Iran: A genomic and phenotypic analysis of clinical isolates, multifactorial resistance mechanisms, and its societal impact
This study underscores the critical convergence of multiple resistance mechanisms (enzymatic degradation, efflux overexpression, porin loss, and biofilm formation) driving the emergence of PDR <i>P. aeruginosa</i> in Iran, necessitating enhanced surveillance and innovative treatment strategies.
Authors
- Ali Hashemi
- Mehdi Goudarzi (ORCID: https://orcid.org/0000-0001-6720-9341)
- Zohreh Ghalavand (ORCID: https://orcid.org/0000-0002-1998-2716)
- Amirhossein Fayyazi (ORCID: https://orcid.org/0000-0002-0383-6722)
- Javad Yasbolaghi Sharahi (ORCID: https://orcid.org/0000-0002-5183-6153)
Institutions
- Shahid Beheshti University of Medical Sciences (IR)
Publication Details
- Journal
- New Microbes and New Infections
- Published
- 2026-03-05
- DOI
- https://doi.org/10.1016/j.nmni.2026.101736
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 0.00