Overdiagnosis of necrotizing fasciitis: clinical–radiological suspicion <i>versus</i> intraoperative findings in 62 fasciotomy patients

Elevated LRINEC scores and advanced clinical signs predict confirmed necrosis but not mortality. The timely decision to perform fasciotomy, regardless of confirmed necrosis, appears to be critical for improving outcomes. This suggests that relying on clinical judgement and early surgical exploration is critical for a timely and effective response to highly suspected cases of NF.

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Publication Details

Journal
Infectious Diseases
Published
2026-03-05
DOI
https://doi.org/10.1080/23744235.2026.2639004
Primary Topic
Streptococcal Infections and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Overdiagnosis of necrotizing fasciitis: clinical–radiological suspicion versus intraoperative findings in 62 fasciotomy patients

Anna Spadoni, Mario Sarti, Giulia Manzini, Erica Franceschini et al.
Infectious Diseases
Streptococcal Infections and Treatments
article

Overdiagnosis of necrotizing fasciitis: clinical–radiological suspicion versus intraoperative findings in 62 fasciotomy patients

Anna Spadoni, Mario Sarti, Giulia Manzini, Erica Franceschini, Mattia Simion, Andrea Bedini, Marianna Meschiari, C Mussini, Valentina Menozzi
article en

Abstract

Elevated LRINEC scores and advanced clinical signs predict confirmed necrosis but not mortality. The timely decision to perform fasciotomy, regardless of confirmed necrosis, appears to be critical for improving outcomes. This suggests that relying on clinical judgement and early surgical exploration is critical for a timely and effective response to highly suspected cases of NF.

Infectious Diseases
Azienda Ospedaliero-Universitaria di Modena (IT), Ospedale Santa Maria (IT)
Good health and well-being
Openalex Percentile: Top 38%
Streptococcal Infections and Treatments
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