Intraoperative sodium range affects white matter microstructure in neonatal congenital heart disease
A larger maximum intraoperative sodium range was associated with reduced axial diffusivity, possibly indicating axonal injury in neonates with CHD after cardiopulmonary bypass surgery. These findings underscore the importance of limiting perioperative osmotic stress to optimize white matter microstructural development.
Authors
- Hanna Talacua (ORCID: https://orcid.org/0009-0000-0805-8862)
- Nathalie H.P. Claessens (ORCID: https://orcid.org/0000-0002-4221-2779)
- Johannes M.P.J. Breur
- Mirthe E. M. van der Meijden (ORCID: https://orcid.org/0009-0003-1248-070X)
- Kim van Loon
- Joppe Nijman
- Serena J Counsell
- Manon J.N.L. Benders
- Maaike Nijman
- Alexandra F. Bonthrone
Institutions
- King's College London (GB)
- University Medical Center Utrecht (NL)
- Wilhelmina Children's Hospital (NL)
Publication Details
- Journal
- International Journal of Cardiology Congenital Heart Disease
- Published
- 2026-03-05
- DOI
- https://doi.org/10.1016/j.ijcchd.2026.100666
- Primary Topic
- Congenital Heart Disease Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00