Targeting the oxidative stress-neuroinflammation axis: the mechanism of arctigenin’s broad-spectrum analgesia with limited side effects

The present study is the first to provide evidences that AG may represent a novel therapeutic target with high analgesic activity and low side effects for the treatment of neuropathic pain.

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Publication Details

Journal
Frontiers in Immunology
Published
2026-03-05
DOI
https://doi.org/10.3389/fimmu.2026.1754756
Primary Topic
Plant-derived Lignans Synthesis and Bioactivity
Type
article
Field-Weighted Citation Impact
0.00
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article

Targeting the oxidative stress-neuroinflammation axis: the mechanism of arctigenin’s broad-spectrum analgesia with limited side effects

Yan Xu, W B Li, Ping Lu, Jinglei Liao et al.
Frontiers in Immunology
Plant-derived Lignans Synthesis and Bioactivity
article

Targeting the oxidative stress-neuroinflammation axis: the mechanism of arctigenin’s broad-spectrum analgesia with limited side effects

Yan Xu, W B Li, Ping Lu, Jinglei Liao, J R Jiang, Chen Lu, Zhe Wang, Shu Li
article en

Abstract

The present study is the first to provide evidences that AG may represent a novel therapeutic target with high analgesic activity and low side effects for the treatment of neuropathic pain.

Frontiers in ImmunologyVol. 17
Shihezi University (CN), Xuzhou University of Technology (CN), Xuzhou Medical College (CN), Xuzhou Children Hospital (CN), Maternal and Child Health Hospital of Xuzhou (CN)
Good health and well-being
Openalex Percentile: Top 33%
Plant-derived Lignans Synthesis and Bioactivity
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