Vicarious learned helplessness: a translationally relevant novel model of stress contagion elucidating sex-dependent prefrontal cortex pathology

Vicarious trauma is sufficient to drive depression-like pathology through distinct molecular trajectories in males and females. These findings are suggestive of the critical necessity for sex-specific therapeutic strategies when treating trauma-related psychiatric disorders.

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Publication Details

Journal
Frontiers in Behavioral Neuroscience
Published
2026-03-05
DOI
https://doi.org/10.3389/fnbeh.2026.1788847
Primary Topic
Stress Responses and Cortisol
Type
article
Field-Weighted Citation Impact
0.00
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article

Vicarious learned helplessness: a translationally relevant novel model of stress contagion elucidating sex-dependent prefrontal cortex pathology

Kalyani Soren, Roli Kushwaha, Shashikant Patel, Debiprasad Sinha et al.
Frontiers in Behavioral Neuroscience
Stress Responses and Cortisol
article

Vicarious learned helplessness: a translationally relevant novel model of stress contagion elucidating sex-dependent prefrontal cortex pathology

Kalyani Soren, Roli Kushwaha, Shashikant Patel, Debiprasad Sinha, Sumana Chakravarty, Arvind Kumar
article en

Abstract

Vicarious trauma is sufficient to drive depression-like pathology through distinct molecular trajectories in males and females. These findings are suggestive of the critical necessity for sex-specific therapeutic strategies when treating trauma-related psychiatric disorders.

Frontiers in Behavioral NeuroscienceVol. 20
Centre for Cellular and Molecular Biology (IN), Indian Institute of Chemical Technology (IN), Academy of Scientific and Innovative Research (IN)
Gender equality
Openalex Percentile: Top 34%
Stress Responses and Cortisol
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