Update on diffuse idiopathic pulmonary neuroendocrine cell hyperplasia

More awareness of DIPNECH is needed among pulmonary clinicians. Apart from the usual presentation of cough with lung nodules and spirometric obstruction in women, patients also present with dyspnea and/or restrictive patterns on PFTs. Variability in diagnosis and management is widespread. Multidisciplinary assessment is helpful in guiding management. Multicenter and multispecialty collaboration is needed to establish best practices and improve clinical management.

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Publication Details

Journal
Current Opinion in Pulmonary Medicine
Published
2026-03-04
DOI
https://doi.org/10.1097/mcp.0000000000001264
Primary Topic
Neuroendocrine Tumor Research Advances
Type
article
Field-Weighted Citation Impact
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article

Update on diffuse idiopathic pulmonary neuroendocrine cell hyperplasia

Peter J. Mazzone, Uddalak Majumdar
Current Opinion in Pulmonary Medicine
Neuroendocrine Tumor Research Advances
article

Update on diffuse idiopathic pulmonary neuroendocrine cell hyperplasia

Peter J. Mazzone, Uddalak Majumdar
article en

Abstract

More awareness of DIPNECH is needed among pulmonary clinicians. Apart from the usual presentation of cough with lung nodules and spirometric obstruction in women, patients also present with dyspnea and/or restrictive patterns on PFTs. Variability in diagnosis and management is widespread. Multidisciplinary assessment is helpful in guiding management. Multicenter and multispecialty collaboration is needed to establish best practices and improve clinical management.

Current Opinion in Pulmonary Medicine
Cleveland Clinic (US)
Openalex Percentile: Top 34%
Neuroendocrine Tumor Research Advances
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Update on diffuse idiopathic pulmonary neuroendocrine cell hyperplasia — Peter J. Mazzone, Uddalak Majumdar · Current Opinion in Pulmonary Medicine (2026) | TGRS Research Map | TGRS