Multi-Omics and Single-Cell Mendelian Randomization Reveal a Potential Role of <i>VNN2</i> in Lung Adenocarcinoma in Resting Natural Killer Cells

Multi-omics and sc-eQTL MR analyses indicated that genetically predicted increases in <i>VNN2</i> expression were associated with a reduced risk of LUAD, with the most pronounced effect observed in rNK cells. These findings suggest a potential cell type-specific role of <i>VNN2</i> in LUAD susceptibility and warrant further studies to validate its biological relevance and clinical implications.