Association of plasma ceramide with stroke-associated pneumonia in acute ischemic stroke
Plasma C16:0-Cer, C18:0-Cer, and CERT1 scores were significantly elevated in patients with AIS and SAP. Among them, C16:0-Cer served as an independent predictor for SAP in AIS patients. It demonstrated moderate predictive accuracy, suggesting its potential as a novel biomarker for early SAP risk stratification.
Authors
- Hui Li (ORCID: https://orcid.org/0000-0001-9198-3951)
- Mi Yang (ORCID: https://orcid.org/0000-0002-1975-3075)
- Yu Bi
- Xinyi Ye
- Ying Sheng
- Mengwen Lu
- Yingying Wang
- Xinyan Guo
- Tianyu Ma
- Zhouao Zhang
- Xue Du
- Xiaoyu Huang
- Yong Zhang
Institutions
- Tongji University (CN)
- Xuzhou Medical College (CN)
- Soochow University (CN)
- Wuxi Ninth People's Hospital (CN)
- Cixian People's Hospital (CN)
- The Fifth People’s Hospital of Suzhou (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2026-03-04
- DOI
- https://doi.org/10.3389/fimmu.2026.1739949
- Primary Topic
- Sphingolipid Metabolism and Signaling
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Government of Jiangsu Province
- Xuzhou Medical University