Learning Continuous Decomposable Models Using Mutual Information and Statistical Copulas

Learning dependence graphs from multivariate continuous data is challenging when marginal distributions are heterogeneous, since likelihood-based nonparametric scores can be sensitive to smoothing choices and can confound marginal irregularities, including non-identifiability, with dependence. This work studies structure learning in the class of decomposable (chordal) Markov random fields, where junction tree factorizations enable tractable inference and local score updates. Our first contribution is a theoretical result showing that, under decomposability, mutual information can be expressed as a difference of clique/separator copula entropies, yielding a dependence-only decomposition aligned with the clique/separator structure. Building on this identity, we define an information-theoretic objective for decomposable graphs with a complexity penalty that preserves clique/separator additivity, and we derive closed-form local score differences for chordality-preserving single-edge insertions and deletions. To make the score computable from data, we instantiate clique/separator copula entropies using pseudo-observations and a probit-transformed kernel density estimator with predictive log score evaluation to mitigate boundary effects on the unit hypercube. The resulting nonparametric greedy procedure improves edge recovery accuracy on synthetic chordal benchmarks compared with a likelihood-driven nonparametric baseline, and it produces interpretable dependence summaries on an airway epithelial gene expression dataset. Concretely, this paper contributes (1) a decomposable mutual information identity via clique/separator copula entropies, (2) a copula information score with an additive complexity penalty for decomposable graphs, (3) a closed-form local score, enabling greedy chordal add or delete search, (4) a practical nonparametric copula entropy estimation pipeline, and (5) empirical gains on synthetic and real data.

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Publication Details

Journal
Entropy
Published
2026-03-04
DOI
https://doi.org/10.3390/e28030293
Primary Topic
Bioinformatics and Genomic Networks
Type
article
Field-Weighted Citation Impact
0.00

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article

Learning Continuous Decomposable Models Using Mutual Information and Statistical Copulas

Carlos Dias Maciel, L. SILVEIRA NETO, Henrique O. Caetano, Matheus de Souza Sant’Anna Fogliatto
Entropy
Bioinformatics and Genomic Networks
article

Learning Continuous Decomposable Models Using Mutual Information and Statistical Copulas

Carlos Dias Maciel, L. SILVEIRA NETO, Henrique O. Caetano, Matheus de Souza Sant’Anna Fogliatto
article en

Abstract

Learning dependence graphs from multivariate continuous data is challenging when marginal distributions are heterogeneous, since likelihood-based nonparametric scores can be sensitive to smoothing choices and can confound marginal irregularities, including non-identifiability, with dependence. This work studies structure learning in the class of decomposable (chordal) Markov random fields, where junction tree factorizations enable tractable inference and local score updates. Our first contribution is a theoretical result showing that, under decomposability, mutual information can be expressed as a difference of clique/separator copula entropies, yielding a dependence-only decomposition aligned with the clique/separator structure. Building on this identity, we define an information-theoretic objective for decomposable graphs with a complexity penalty that preserves clique/separator additivity, and we derive closed-form local score differences for chordality-preserving single-edge insertions and deletions. To make the score computable from data, we instantiate clique/separator copula entropies using pseudo-observations and a probit-transformed kernel density estimator with predictive log score evaluation to mitigate boundary effects on the unit hypercube. The resulting nonparametric greedy procedure improves edge recovery accuracy on synthetic chordal benchmarks compared with a likelihood-driven nonparametric baseline, and it produces interpretable dependence summaries on an airway epithelial gene expression dataset. Concretely, this paper contributes (1) a decomposable mutual information identity via clique/separator copula entropies, (2) a copula information score with an additive complexity penalty for decomposable graphs, (3) a closed-form local score, enabling greedy chordal add or delete search, (4) a practical nonparametric copula entropy estimation pipeline, and (5) empirical gains on synthetic and real data.

EntropyVol. 28(3)
Universidade de São Paulo (BR), Universidade Estadual Paulista (Unesp) (BR)
Fundação de Amparo à Pesquisa do Estado de São Paulo, Coordenação de Aperfeiçoamento de Pessoal de Nível Superior, Conselho Nacional de Desenvolvimento Científico e Tecnológico
Openalex Percentile: Top 33%
Bioinformatics and Genomic Networks
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