Integrative genomic analysis of missense mutations and target genes in hemorrhoid pathogenesis
Hemorrhoids are a prevalent anorectal condition characterized by the enlargement and displacement of anal cushions. While environmental and lifestyle factors are well-established contributors, emerging evidence suggests a genetic predisposition involving connective tissue integrity and smooth muscle dysfunction. However, the specific genetic variants contributing to hemorrhoid pathogenesis remain largely undefined.
Authors
- Muhammad Yulis Hamidy (ORCID: https://orcid.org/0000-0003-3412-4063)
- Lalu Muhammad Irham (ORCID: https://orcid.org/0000-0002-0091-4887)
- Wirawan Adikusuma (ORCID: https://orcid.org/0000-0001-9165-690X)
- Ismawati Ismawati
- Alauddin Syaifulanwar
- Lian Pajrianti
- Darmawi Darmawi
Institutions
- Universitas Ahmad Dahlan (ID)
- Universitas Abdurrab (ID)
- National Nuclear Energy Agency of Indonesia (ID)
- National Research and Innovation Agency (ID)
- Riau University (ID)
Publication Details
- Journal
- Folia Medica
- Published
- 2026-02-26
- DOI
- https://doi.org/10.3897/folmed.68.e166557
- Primary Topic
- Anorectal Disease Treatments and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.00