Clinical phenotype and molecular characteristics of carbapenem-resistant hypervirulent Klebsiella pneumoniae causing multi-site infection

The three clinically isolated <i>K. pneumoniae</i> strains were highly virulent and carbapenem-resistant, all carrying the <i>KPC</i> resistance gene. They caused multi-site infections through hematogenous dissemination. These findings highlight the need for heightened clinical vigilance and strengthened monitoring, prevention, and control of drug-resistant infections.

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Publication Details

Journal
Frontiers in Microbiology
Published
2026-03-04
DOI
https://doi.org/10.3389/fmicb.2026.1771186
Primary Topic
Antibiotic Resistance in Bacteria
Type
article
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article

Clinical phenotype and molecular characteristics of carbapenem-resistant hypervirulent Klebsiella pneumoniae causing multi-site infection

Jing Su, Hengzhong Lun, Fenfen Liu, Meijie Jiang
Frontiers in Microbiology
Antibiotic Resistance in Bacteria
article

Clinical phenotype and molecular characteristics of carbapenem-resistant hypervirulent Klebsiella pneumoniae causing multi-site infection

Jing Su, Hengzhong Lun, Fenfen Liu, Meijie Jiang
article en

Abstract

The three clinically isolated <i>K. pneumoniae</i> strains were highly virulent and carbapenem-resistant, all carrying the <i>KPC</i> resistance gene. They caused multi-site infections through hematogenous dissemination. These findings highlight the need for heightened clinical vigilance and strengthened monitoring, prevention, and control of drug-resistant infections.

Frontiers in MicrobiologyVol. 17
Qingdao University (CN), Affiliated Hospital of Qingdao University (CN), Taian City Central Hospital (CN)
Good health and well-being
Openalex Percentile: Top 33%
Antibiotic Resistance in Bacteria
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