A meta-analysis of smoking and fracture risk to update the FRAX® tool

Our results confirm the association between current smoking and increased fracture risk that is partly independent of BMD; these data will be used to inform future iterations of FRAX.

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Publication Details

Journal
Osteoporosis International
Published
2026-03-04
DOI
https://doi.org/10.1007/s00198-026-07853-6
Primary Topic
Bone health and osteoporosis research
Type
article
Field-Weighted Citation Impact
0.00
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article

A meta-analysis of smoking and fracture risk to update the FRAX® tool

F A Anderson, Alyssa B. Dufour, Mark A. Kotowicz, Serge Ferrari et al.
Osteoporosis International
Bone health and osteoporosis research
article

A meta-analysis of smoking and fracture risk to update the FRAX® tool

F A Anderson, Alyssa B. Dufour, Mark A. Kotowicz, Serge Ferrari, Rosemary Hollick, Jose ́ A. P. da Silva, A.-M. Schott, DAN MELLSTROM, Berit Schei, R. Chapurlat, Stephen Cummings, Heike A. Bischoff‐Ferrari, Martijn Huisman, Marian Schini, JUNKO TAMAKI, Cecilie L. Bager, Peter Nordström, Thomas Merlijn, E. Sornay‐Rendu, Jill J. Hall, B Obermayer-Pietsch, T. van Staa, Magnus K. Karlsson, K. Åkesson, T. O’neill, Kurt Lippuner, MCarola Zillikens, Masayuki Iki, Sophia Ish-Shalom, Yuki Fujita, Joan Vila, Julie A. Pasco, C. Christiansen, K. Siggeirsdóttir, Glüer Cc, Enwu Liu, Douglas P Kiel, Reijo Sund, Graeme Jones, Sundeep Khosla, Pawel Szulc, H. Johansson, N C Harvey, Eric S Orwoll, V Gudnason, Karin MA Swart, Noriko Yoshimura, Carolyn J. Crandall, Anne-Marie Schott, Nicole C. Wright, Bagher Larijani, Olivier Lamy, Nicholas J. Wareham, Tuan V. Nguyen, Cyrus Cooper, John A. Eisman, Jane A. Cauley, Anna Nordström, Eugene V. McCloskey, Claes Ohlsson, Bess Dawson-Hughes, Woon-Puay Koh, Timothy Kwok, Emmanuel Biver, Natasja M. van Schoor, Mari Hoff, Eleanor M. Simonsick, Mattias Lorentzon, Rafael Azagra-Ledesma, Heikki Kröger, Marta Zwart, David Goltzman, Arnulf Langhammer, William D. Leslie, Inbal Goldshtein, Didier Hans, Saeko Fujiwara, John A. Kanis
article en

Abstract

Our results confirm the association between current smoking and increased fracture risk that is partly independent of BMD; these data will be used to inform future iterations of FRAX.

Osteoporosis International
Université Claude Bernard Lyon 1 (FR), University of Technology Sydney (AU), Tulane University (US), University of Bern (CH), Tufts University (US), Universitat Autònoma de Barcelona (ES), Uppsala University (SE), Kansai Medical University (JP), The University of Sydney (AU), University of Tasmania (AU), Beth Israel Deaconess Medical Center (US), Barwon Health (AU), Institut Català d'Ornitologia (ES), Garvan Institute of Medical Research (AU), Deakin University (AU), University of Namur (BE), Inserm (FR), University of Liège (BE), Tokyo Medical University (JP), University of California, Los Angeles (US), Tel Aviv University (IL), University of Iceland (IS), Oregon Health & Science University (US), The University of Melbourne (AU), National University of Singapore (SG), University of Massachusetts Chan Medical School (US), Flinders University (AU), University of Pittsburgh (US), University of Eastern Finland (FI), Chinese University of Hong Kong (HK), Lund University (SE), University of Aberdeen (GB), Medical University of Graz (AT), University of Zurich (CH), Norwegian University of Science and Technology (NO), University of Cambridge (GB), Universitat de Girona (ES), Catalan Institute for Water Research (ES), Manchester Academic Health Science Centre (GB), Levanger Hospital (NO), Sahlgrenska University Hospital (SE), McGill University Health Centre (CA), California Pacific Medical Center (US), Erasmus MC (NL), University Hospital Southampton NHS Foundation Trust (GB), University of Manchester (GB), UNSW Sydney (AU), Christian-Albrechts-Universität zu Kiel (DE), University of Oxford (GB), Kuopio University Hospital (FI), Region Västra Götaland (SE), Hong Kong Jockey Club (HK), Singapore Institute for Clinical Sciences (SG), St Olav's University Hospital (NO), University Hospital of Geneva (CH), Pasqual Maragall Foundation (ES), Amsterdam Neuroscience (NL), Jean Mayer Human Nutrition Research Center on Aging (US), Centro de Investigación Biomédica en Red (ES), Felix Platter-Hospital (CH), MRC Centre for Reproductive Health (GB), Western Health (AU), Arthritis UK (GB), NIHR Southampton Biomedical Research Centre (GB), Pharmo Institute (NL), St Vincent's Clinic (AU), Hôpital Edouard Herriot (FR), Hebrew SeniorLife (US), Mayo Clinic in Arizona (US), Institut Universitari d'Investigació en Atenció Primària Jordi Gol (ES), Hospital Del Mar (ES), National Institute on Aging (US), Skåne University Hospital (SE), Nordic Bioscience (Denmark) (DK), Oxford BioMedica (United Kingdom) (GB), MRC Lifecourse Epidemiology Unit (GB), GGD Amsterdam (NL), Amsterdam University Medical Centers (NL), Icelandic Heart Association (IS), Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública (ES), Elisha Hospital (IL), Hospital del Mar Research Institute (ES), MRC Epidemiology Unit (GB), NIHR Manchester Biomedical Research Centre (GB), Clinical Research Center Kiel (DE), Maccabi Institute for Health Services Research (IL), University of Southampton (GB), University of Manitoba (CA), University of York (GB), Monash University (AU), Geneva College (US), Tehran University of Medical Sciences (IR), Yasuda Women's University (JP), University of Coimbra (PT), UiT The Arctic University of Norway (NO), Vrije Universiteit Amsterdam (NL), University of Gothenburg (SE), University of Amsterdam (NL), Osaka University of Pharmaceutical Sciences (JP), University of Sheffield (GB), Kindai University (JP), The University of Notre Dame Australia (AU), University of Lausanne (CH), University of Edinburgh (GB)
Good health and well-being
Openalex Percentile: Top 35%
Bone health and osteoporosis research
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