Prevalence of and risk factors for antimicrobial resistance in pneumococcal disease in southern Ontario during the PCV13 era

In our population, pneumococcal antimicrobial resistance has remained relatively stable, but changes differ by antibiotic class. Implementation of vaccination programs with PCV20 or PCV21 should reduce AMR by disease prevention.

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Publication Details

Journal
Vaccine
Published
2026-03-04
DOI
https://doi.org/10.1016/j.vaccine.2026.128351
Primary Topic
Pneumonia and Respiratory Infections
Type
article
Field-Weighted Citation Impact
0.00
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article

Prevalence of and risk factors for antimicrobial resistance in pneumococcal disease in southern Ontario during the PCV13 era

George Zhanel, Karen A. Green, Altynay Shigayeva, Angel Xinliu Li et al.
Vaccine
Pneumonia and Respiratory Infections
article

Prevalence of and risk factors for antimicrobial resistance in pneumococcal disease in southern Ontario during the PCV13 era

George Zhanel, Karen A. Green, Altynay Shigayeva, Angel Xinliu Li, Tamara Vikulova, Brenda L. Coleman, Alyssa Golden, Lubna Farooqi, Sarah Nayani, Maxime Lefebvre, Zoë Zhong, Neil Rau, Reena Lovinsky, Kevin Katz, Amna Faheem, Daniel Ricciuto, Christie Vermeiren, Asfia Sultana, Irene Martin, David Richardson, Kazi Hassan, Krystyna Ostrowska, Christopher Kandel, Agron Plevneshi, Allison McGeer, Nadia Malik, Matthew P. Muller, Wayne L. Gold, Heather Adam
article en

Abstract

In our population, pneumococcal antimicrobial resistance has remained relatively stable, but changes differ by antibiotic class. Implementation of vaccination programs with PCV20 or PCV21 should reduce AMR by disease prevention.

VaccineVol. 78
University Health Network (CA), Public Health Agency of Canada (CA), University of Toronto (CA), Scarborough Health Network (CA), Lakeridge Health (CA), North York General Hospital (CA), Trillium Health Centre (CA), Toronto General Hospital (CA), Toronto East General Hospital (CA), Public Health Ontario (CA), William Osler Health System (CA), Sinai Health System (CA), HalTech (CA), University of Manitoba (CA)
Good health and well-being
Openalex Percentile: Top 35%
Pneumonia and Respiratory Infections
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