Predicting a metachronous cutaneous squamous cell carcinoma: a competing-risk model based on nationwide linked registries
this competing-risk model provides individualized, well-calibrated absolute risk estimates for a first metachronous CSCC. Based on routinely available clinical features, it offers insight into how established predictors shape risk in this high-susceptibility population and quantifies relative risk acceleration. External validation and the identification of novel predictors are necessary to further refine the model and support personalized surveillance strategies.
Authors
- Celeste J Eggermont (ORCID: https://orcid.org/0000-0002-1669-0283)
- Andrya Reder Hollatz (ORCID: https://orcid.org/0000-0002-9211-822X)
- Loes M. Hollestein (ORCID: https://orcid.org/0000-0001-8922-6791)
- Barbara Rentroia-Pacheco
- Marlies Wakkee
- Tamar Nijsten
- Marieke Louwman
- Antien Mooyaart
Institutions
- University Medical Center (US)
- Netherlands Comprehensive Cancer Organisation (NL)
- Erasmus MC Cancer Institute (NL)
Publication Details
- Journal
- British Journal of Dermatology
- Published
- 2026-03-02
- DOI
- https://doi.org/10.1093/bjd/ljag076
- Primary Topic
- Nonmelanoma Skin Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00