Tenecteplase versus alteplase as bridging therapy before endovascular treatment in acute ischemic stroke due to Basilar artery occlusion: a systematic review and meta-analysis

In BAO, tenecteplase as bridging therapy prior to EVT improves early and final reperfusion without increasing hemorrhagic risk or mortality, with functional outcomes comparable to alteplase, although the current evidence is limited.

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Publication Details

Journal
Neurological Research
Published
2026-03-03
DOI
https://doi.org/10.1080/01616412.2026.2640114
Primary Topic
Acute Ischemic Stroke Management
Type
article
Field-Weighted Citation Impact
0.00
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article

Tenecteplase versus alteplase as bridging therapy before endovascular treatment in acute ischemic stroke due to Basilar artery occlusion: a systematic review and meta-analysis

J. Mancha Ramos, João Vítor Andrade Fernandes, Gabriel Caruso Novaes Tudella, Maurus Marques de Almeida Holanda
Neurological Research
Acute Ischemic Stroke Management
article

Tenecteplase versus alteplase as bridging therapy before endovascular treatment in acute ischemic stroke due to Basilar artery occlusion: a systematic review and meta-analysis

J. Mancha Ramos, João Vítor Andrade Fernandes, Gabriel Caruso Novaes Tudella, Maurus Marques de Almeida Holanda
article en

Abstract

In BAO, tenecteplase as bridging therapy prior to EVT improves early and final reperfusion without increasing hemorrhagic risk or mortality, with functional outcomes comparable to alteplase, although the current evidence is limited.

Neurological Research
Universidade Federal da Paraíba (BR), Universidade Federal de Santa Maria (BR)
Good health and well-being
Openalex Percentile: Top 35%
Acute Ischemic Stroke Management
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