Case Report: Molecular diagnostics and clinical courses of two adult spinal pilocytic astrocytoma long-term survivors with GTF2I::BRAF fusion
To our knowledge, this is only the second case series highlighting a unique GTF2I::BRAF fusion and the first to describe it in adults in a spinal location. The manuscript contributes documentation of a rare fusion and tumor presentation to guide clinicians and potential research avenues.
Authors
- Anna Choi (ORCID: https://orcid.org/0000-0002-9341-8515)
- Nathan Clarke (ORCID: https://orcid.org/0000-0002-3595-3800)
- Marissa L. Panzer
- Jacob Mandel (ORCID: https://orcid.org/0000-0001-5916-5668)
- Hsiang-Chih Lu
- Lorenzo Argao
- Renee Tweneboah-Koduah
- Michelle L Cassidy
- Marta Penas-Prado
- Pinar E. Zerk
- Kenneth Aldape
- Byram H. Ozer
- Bennett Mclver
- Paul Park
- Martha Quezado
Institutions
- Emory University (US)
- Baylor College of Medicine (US)
- University of Michigan (US)
- Cancer Institute (WIA) (IN)
- National Cancer Institute (MY)
- Sylvester Comprehensive Cancer Center (US)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2026-03-04
- DOI
- https://doi.org/10.3389/fonc.2026.1670639
- Primary Topic
- Glioma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institutes of Health
- National Cancer Institute