Overexpression of TFF3 is Associated with Immune Infiltration, Molecular Subtypes, and Clinical Progression in Breast Cancer

TFF3 is a robust diagnostic biomarker for BRCA molecular subtyping, an independent prognostic factor, and a potential immunomodulator. These findings highlight its clinical utility for patient stratification and potential as a therapeutic target, particularly in hormone receptor-positive BRCA.

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Publication Details

Journal
Current Medical Science
Published
2026-03-04
DOI
https://doi.org/10.1007/s11596-026-00173-0
Primary Topic
Helicobacter pylori-related gastroenterology studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Overexpression of TFF3 is Associated with Immune Infiltration, Molecular Subtypes, and Clinical Progression in Breast Cancer

Han-Han Liu, R. Stephanie Huang, Ziming Huang, Junbo Hu et al.
Current Medical Science
Helicobacter pylori-related gastroenterology studies
article

Overexpression of TFF3 is Associated with Immune Infiltration, Molecular Subtypes, and Clinical Progression in Breast Cancer

Han-Han Liu, R. Stephanie Huang, Ziming Huang, Junbo Hu, Qin Wang, Hui Xu, Xiao-hong Min, Huan Wu, Bei Liu, Yong-qing Tong
article en

Abstract

TFF3 is a robust diagnostic biomarker for BRCA molecular subtyping, an independent prognostic factor, and a potential immunomodulator. These findings highlight its clinical utility for patient stratification and potential as a therapeutic target, particularly in hormone receptor-positive BRCA.

Current Medical Science
Fujian Medical University (CN), Hubei Provincial Women and Children's Hospital (CN), Second Affiliated Hospital of Fujian Medical University (CN)
Good health and well-being
Openalex Percentile: Top 34%
Helicobacter pylori-related gastroenterology studies
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