Untargeted metabolomics data in the By-Band-Sleeve trial and ALSPAC: integrating clinical trial and population cohort data
Overall, we have provided a summary of MS data produced across two different study populations, described the QC procedures undertaken and provided some data validation analyses. Bringing together samples from these two studies in a single experiment offers a novel study design able to explore the biological implications of weight and intentional weight loss.
Authors
- Chris W. Rogers (ORCID: https://orcid.org/0000-0002-4253-1825)
- Sophie FitzGibbon
- Lucy J. Goudswaard (ORCID: https://orcid.org/0000-0003-1481-6871)
- Eleanor Gidman (ORCID: https://orcid.org/0000-0002-5261-5213)
- Laura J. Corbin (ORCID: https://orcid.org/0000-0002-4032-9500)
- Gail White (ORCID: https://orcid.org/0009-0006-5455-5337)
- Susan Ring
- Alix Groom
- Kate Northstone
- Laurie Fabian
- Madeleine Smith
- Jane Blazeby
- David Hughes
- Nicholas J. Timpson
- Sarah Matthews
Institutions
- Pennington Biomedical Research Center (US)
- University Hospitals Bristol NHS Foundation Trust (GB)
- University of Bristol (GB)
- NIHR Bristol Biomedical Research Centre (GB)
- MRC Epidemiology Unit (GB)
- University Hospitals Bristol and Weston NHS Foundation Trust (GB)
Publication Details
- Journal
- Wellcome Open Research
- Published
- 2026-03-04
- DOI
- https://doi.org/10.12688/wellcomeopenres.24917.2
- Primary Topic
- Metabolomics and Mass Spectrometry Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- NIHR Bristol Biomedical Research Centre
- National Institute for Health and Care Research
- University of Bristol