Anticoagulant-free preparation of autologous platelet-rich plasma (PRP) / fluid platelet-rich fibrin (f-PRF): a pre-clinical comparative performance study

These findings support the Exprecell™ single soft-spin methodology, demonstrating that anticoagulant-free f-PRF preparation achieves functional equivalence to conventional methods while providing a statistically significant increase in volume yield and procedural simplicity. The closed system design reduces contamination risk and Luer-lock compatibility facilitates integration into clinical workflows. Maintained <i>in vitro</i> biological activity supports clinical utility for this innovative point-of-care f-PRF preparation device. Future studies are needed to demonstrate the clinical benefit of the f-PRF obtained.